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E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF640R conjugate, 0.1mg/mL [26628-22-8]

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC402208
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Rabbit
TargetCDH1
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Overview

  • Supplier
    Biotium
  • Product Name
    E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CDH1/2208R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID999
  • Target name
    CDH1
  • Target description
    cadherin 1
  • Target synonyms
    Arc-1; BCDS1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); cadherin-1; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDHE; cell-CAM 120/80; ECAD; E-cadherin 1; epididymis secretory sperm binding protein; epithelial cadherin; LCAM; UVO; uvomorulin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP12830
  • Protein Name
    Cadherin-1
  • Scientific Description
    This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin ) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Rabbit
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203