(E)-Guanabenz

MedChem Express

(E)-Guanabenz

10

Research Use Only

C8H8Cl2N4

231.08

(E)-Guanabenz ((E)-Wy-8678) is an orally active central alpha2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts via stimulating central alpha2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease [1] [2] .

ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1

12352200