More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/(E)-KPT-330 [1421923-86-5]

(E)-KPT-330 [1421923-86-5]

K6276
LKT Laboratories
Estimated Purity≥99%
DownloadDatasheet
Product group Chemicals
€ 127,00
1 mg
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    LKT Laboratories
  • Product Name
    (E)-KPT-330 [1421923-86-5]
  • Delivery Days Customer
    7
  • Estimated Purity
    ≥99%
  • Format
    DMSO 88 mg/mL (198.5 mM); Ethanol 40 mg/mL (90.23 mM); Water Insoluble
  • Scientific Description
    CRM1-selective inhibitor of nuclear export.; Selinexor E-isomer, Selinexor trans-isomer, KPT-330 E-isomer, E-KPT-330
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Ishizawa J, Kojima K, Hail N Jr, et al. Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein. Pharmacol Ther. 2015 Jun 3. [Epub ahead of print]. PMID: 26048327. De Cesare M, Cominetti D, Doldi V, et al. Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin. Oncotarget. 2015 May 30;6(15):13119-32. PMID: 25948791. Parikh K, Cang S, Sekhri A, et al. Selective inhibitors of nuclear export (SINE)--a novel class of anti-cancer agents. J Hematol Oncol. 2014 Oct 15;7:78. PMID: 25316614.