E3 Ligase Ligand-linker Conjugate 10

MedChem Express

E3 Ligase Ligand-linker Conjugate 10

14

Research Use Only

C25H32N4O6

484.54

Thalidomide-O-C4H4-N(Me)-piperidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-C2-OH can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(O[C@@H]4C[C@H](C4)N(C)C5CCN(CC5)CCO)=C3)C2=O)=O)=O

12352200