E3 Ligase Ligand-linker Conjugate 19

MedChem Express

E3 Ligase Ligand-linker Conjugate 19

14

Research Use Only

C33H45N5O7

623.74

Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CC5(CN(CC5)CC6CCN(CC6)CCOCC(OC(C)(C)C)=O)C4)=C3)C2=O)=O)=O

12352200