E3 Ligase Ligand-linker Conjugate 21

MedChem Express

E3 Ligase Ligand-linker Conjugate 21

14

Research Use Only

C26H33N5O5

495.57

Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)CN5CC6(CN(C6)CCO)C5)=C3)C2=O)=O)=O

12352200