E3 Ligase Ligand-linker Conjugate 22

MedChem Express

E3 Ligase Ligand-linker Conjugate 22

14

Research Use Only

C24H31N5O6

485.53

Thalidomide-azetidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CC(C4)N5CCN(CC5)CCOCCO)=C3)C2=O)=O)=O

12352200