E3 Ligase Ligand-linker Conjugate 23

MedChem Express

E3 Ligase Ligand-linker Conjugate 23

14

Research Use Only

C29H38N4O7

554.63

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(O[C@H]4C[C@@H](C4)N(C)C5CCN(CC5)CC(OC(C)(C)C)=O)=C3)C2=O)=O)=O

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