E3 Ligase Ligand-linker Conjugate 24

MedChem Express

E3 Ligase Ligand-linker Conjugate 24

14

Research Use Only

C28H37N5O6

539.62

Thalidomide-piperazine-(R)-C-pyrrolidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-(R)-C-pyrrolidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)C[C@@H]5CN(CC5)CC(OC(C)(C)C)=O)=C3)C2=O)=O)=O

12352200