E3 Ligase Ligand-linker Conjugate 3

MedChem Express

E3 Ligase Ligand-linker Conjugate 3

14

Research Use Only

C25H35N5O4

469.58

Deoxy-thalidomide-piperidine-C-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Deoxy-thalidomide-piperidine-C-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=C(C=C3)N4CCC(CC4)CN5CCN(CC5)CCO)C2)=O)=O

12352200