E3 ligase Ligand-Linker Conjugate 33

MedChem Express

E3 ligase Ligand-Linker Conjugate 33

14

Research Use Only

C31H41N5O6

579.69

Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CC5(CN(C5)CC6CCN(CC6)CC(OC(C)(C)C)=O)CC4)=C3)C2=O)=O)=O

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