E3 ligase Ligand-Linker Conjugate 36

MedChem Express

E3 ligase Ligand-Linker Conjugate 36

14

Research Use Only

C29H39N5O6

553.65

Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CC5(CN(CC5)CC6CCN(CC6)CCOCCO)C4)=C3)C2=O)=O)=O

12352200