E3 Ligase Ligand-linker Conjugate 52

MedChem Express

E3 Ligase Ligand-linker Conjugate 52

14

Research Use Only

C23H29N5O5

455.51

Thalidomide-piperazine-C-azetidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-C-azetidine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)CC5CN(C5)CCO)=C3)C2=O)=O)=O

12352200