E3 Ligase Ligand-linker Conjugate 63

MedChem Express

E3 Ligase Ligand-linker Conjugate 63

14

Research Use Only

C36H48N6O6S

692.87

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.

O=C([C@H]1N(C[C@@H](C1)O)C(C(C(C)C)C2=CC(N3CC4(CCN(CC4)C(OC(C)(C)C)=O)C3)=NO2)=O)NCC(C=C5)=CC=C5C(SC=N6)=C6C

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