E3 Ligase Ligand-linker Conjugate 73

MedChem Express

E3 Ligase Ligand-linker Conjugate 73

14

Research Use Only

C27H35N5O6

525.60

Thalidomide-PIP-(R)C-pyrrolidine-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-PIP-(R)C-pyrrolidine-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)C[C@@H]5CN(CC5)C(OC(C)(C)C)=O)=C3)C2=O)=O)=O

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