E3 Ligase Ligand-linker Conjugate 78

MedChem Express

E3 Ligase Ligand-linker Conjugate 78

14

Research Use Only

C29H39N5O6

553.65

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CC[C@@H]1N2C(C3=C(C=CC(N4CCN(CC4)C[C@H]5CC[C@@H](CC5)NC(OC(C)(C)C)=O)=C3)C2=O)=O)=O

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