E3 Ligase Ligand-linker Conjugate 80

MedChem Express

E3 Ligase Ligand-linker Conjugate 80

14

Research Use Only

C31H41N5O6

579.69

(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4C[C@H]5N([C@H](CC5)C4)C[C@H]6CC[C@@H](CC6)NC(OC(C)(C)C)=O)=C3)C2=O)=O)=O

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