E3 Ligase Ligand-linker Conjugate 82

MedChem Express

E3 Ligase Ligand-linker Conjugate 82

14

Research Use Only

C36H49N5O8S

711.87

PROTAC PTK6 ligand-O-C2-O-piperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-O-C2-O-piperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.

O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)C)C2=CC(OCCOC3CCN(CC3)C(OC(C)(C)C)=O)=NO2)=O)NCC(C=C4)=CC=C4C(SC=N5)=C5C

12352200