E3 Ligase Ligand-linker Conjugate 95

MedChem Express

E3 Ligase Ligand-linker Conjugate 95

14

Research Use Only

C23H26N4O7

470.48

Thalidomide-piperidine-O-azetidine-acetic acid is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-O-azetidine-acetic acid can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)OC5CN(C5)CC(O)=O)=C3)C2=O)=O)=O

12352200