E4177

MedChem Express

E4177

9

Research Use Only

C24H21N3O2

383.44

E4177 (57G709) is an orally active angiotensin II receptor antagonist. E4177 can inhibit the growth of vascular smooth muscle cells (HASMC) and the increase of cell surface area. In addition, E4177 can also increase the expression of platelet-derived growth factor ( PDGF ) receptor. E4177 can be used in the study of vascular diseases [1] .

O=C(C1=C(C2=CC=C(CN3C4=NC=CC(C)=C4N=C3C5CC5)C=C2)C=CC=C1)O

12352200