Ebola virus Glycoprotein/GP (QDA39862, HEK293, His)

MedChem Express

Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His)

10

Research Use Only

90.0

Ebola virus Glycoprotein/GP Protein is pivotal in viral entry, serving as the receptor-binding subunit. In later infection stages, GP1 down-regulates crucial host cell surface molecules, including integrins like ITGA1-6, disrupting adhesion and potentially causing blood vessel integrity disruption. GP1 interacts with host TLR4, stimulating monocyte differentiation, leading to T-lymphocyte bystander death. It down-regulates natural killer cell function, counters BST2/tetherin, cooperates with VP40 for NF-kappa-B activation, acts as an antibody decoy, and induces cytokine transcription in host macrophages and dendritic cells through TLR4 activation. Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His) is the recombinant Virus-derived Ebola virus Glycoprotein/GP protein, expressed by HEK293 , with C-His labeled tag. The total length of Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His) is 650 a.a., with molecular weight of 92-120 & 23-25 kDa, respectively.

-80°C

12352202