Echistatin [154303-05-6]

TargetMol Chemicals

Echistatin [154303-05-6]

44

154303-05-6

Chemical

Echistatin

C217H341N71O74S9

5417.1

Potent irreversible alphaVbeta3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, alphaIIbbeta3) receptors (IC50 = 30 nM) in vitro.

3 years

-20°C

12352200