Ecopipam (hydrobromide)

MedChem Express

Ecopipam (hydrobromide)

10

Research Use Only

99.0

C19H21BrClNO

394.73

Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and alpha2a receptor (K i =0.98, 5.52, 0.08, and 0.73 microM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity [1] .

CN1[C@]2([H])[C@@](C3=CC=CC=C3CC2)([H])C4=CC(O)=C(Cl)C=C4CC1.Br

-20°C

12352200