EDEM1 antibody

GeneTex

EDEM1 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1.21 mg/ml

Unconjugated

EDEM1

ER degradation enhancing alpha-mannosidase like protein 1

EDEM; ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1

Rabbit

IgG

ER degradation-enhancing alpha-mannosidase-like protein 1

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.

Human

-20°C or -80°C,2°C to 8°C

12352203