The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA066402(EDN3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA066402(EDN3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
EDN3 Antibody
CSB-PA066402
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEDN3
Overview
- SupplierCusabio
- Product NameEDN3 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1908
- Target nameEDN3
- Target descriptionendothelin 3
- Target synonymsendothelin-3; ET3; ET-3; HSCR4; PPET3; preproendothelin-3; WS4B
- HostRabbit
- IsotypeIgG
- Protein IDP14138
- Protein NameEndothelin-3
- Scientific DescriptionThe protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203