EEF1E1 Polyclonal Antibody

Reddot Biotech

EEF1E1 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot

Research Use Only

1 mg/ml

Unconjugated

EEF1E1

eukaryotic translation elongation factor 1 epsilon 1

AIMP3; aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; ARS-interacting multifunctional protein 3; eukaryotic translation elongation factor 1 epsilon-1; multisynthase complex auxiliary component p18; P18; p18 component of aminoacyl-tRNA synthetase complex

Rabbit

IgG

This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Human, Mouse, Rat

-20°C

12352203