EFNB1 Polyclonal Antibody

Reddot Biotech

EFNB1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

EFNB1

ephrin B1

CFND; CFNS; EFB1; EFL3; ELK ligand; Elk-L; eph-related receptor tyrosine kinase ligand 2; ephrin-B1; EPLG2; LERK2

Rabbit

IgG

Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Human, Mouse, Rat

-20°C

12352203