EFNB1 Polyclonal Antibody
RD253525A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEFNB1
Overview
- SupplierReddot Biotech
- Product NameEFNB1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.9 mg/ml
- ConjugateUnconjugated
- Gene ID1947
- Target nameEFNB1
- Target descriptionephrin B1
- Target synonymsCFND; CFNS; EFB1; EFL3; ELK ligand; Elk-L; eph-related receptor tyrosine kinase ligand 2; ephrin-B1; EPLG2; LERK2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionEphrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203