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FACS analysis of A431 cells using GTX20231 EGFR antibody [ICR10].
FACS analysis of A431 cells using GTX20231 EGFR antibody [ICR10].
FACS analysis of A431 cells using GTX20231 EGFR antibody [ICR10].

EGFR antibody [ICR10]

Research Use Only
GTX20231
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetEGFR
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Overview

  • Supplier
    GeneTex
  • Product Name
    EGFR antibody [ICR10]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody, clone ICR10 binds to epitope B from EGFR
  • Application Supplier Note
    FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ICR10
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID1956
  • Target name
    EGFR
  • Target description
    epidermal growth factor receptor
  • Target synonyms
    avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP00533
  • Protein Name
    Epidermal growth factor receptor
  • Scientific Description
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression. Scheidmann MC et al., 2022 Feb 15, Cancer Res
    Read more
  • Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells. Donato C et al., 2020 Sep 8, Cell Rep
    Read more
  • Neutrophils escort circulating tumour cells to enable cell cycle progression. Szczerba BM et al., 2019 Feb, Nature
    Read more
  • Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding. Gkountela S et al., 2019 Jan 10, Cell
    Read more
  • Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer. Vetter M et al., 2018 Nov 20, Breast Cancer Res
    Read more