CgoaEWY7REKELxM5AAAAAJ2BSCI164.png
CgoaEWY7REKELxM5AAAAAJ2BSCI164.png
EGFR-IN-5 [2225887-26-1]
T11160
Overview
- SupplierTargetMol Chemicals
- Product NameEGFR-IN-5 [2225887-26-1]
- Delivery Days Customer10
- CAS Number2225887-26-1
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameEGFR-IN-5
- Molecular FormulaC31H38FN9O
- Molecular Weight571.69
- Scientific DescriptionEGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.
- Shelf life instruction3 years
- SMILESN(C=1N=C(C2=C(N1)C=NC(NC3=CC=C(C=N3)N4CCC(N(C)C)CC4)=C2)N5CCC(CO)CC5)C6=CC=C(F)C=C6
- Storage Instruction-20°C
- UNSPSC51202000
References
- Zhang H, et al. Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. Eur J Med Chem. 2018 Mar 25;148:221-237.Read more