EGFR T790M/L858R-IN-8 [333419-97-9]

TargetMol Chemicals

EGFR T790M/L858R-IN-8 [333419-97-9]

9

Research Use Only

C16H11BrN2O3

359.17

EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 microM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.

O=C(NC=1C=CC=C(Br)C1)C=2C(=O)NC=3C=CC=CC3C2O

-20°C

51202000