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EGFR/HER2/DHFR-IN-1

Research Use Only
HY-151154
MedChem Express
Molecular Weight379.23
Product group Chemicals

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Overview

  • Supplier
    MedChem Express
  • Product Name
    EGFR/HER2/DHFR-IN-1
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C14H11BrN4O2S
  • Molecular Weight
    379.23
  • Scientific Description
    EGFR/HER2/DHFR-IN-1 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2/DHFR-IN-1 is a multiple inhibitor of EGFR/HER2 kinase and DHFR, with IC50s of 0.153 microM, 0.108 microM, 0.291 microM, respectively. EGFR/HER2/DHFR-IN-1 arrests cell cycle at G1/S and induces cells apoptosis.
  • SMILES
    O=C(C1=CSC2=NC=C(C3=CC=C(Br)C=C3)N21)NNC(C)=O
  • Storage Instruction
    See Manual
  • UNSPSC
    12352200