EGFR/HER2/DHFR-IN-1

MedChem Express

EGFR/HER2/DHFR-IN-1

10

Research Use Only

C14H11BrN4O2S

379.23

EGFR/HER2/DHFR-IN-1 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2/DHFR-IN-1 is a multiple inhibitor of EGFR/HER2 kinase and DHFR, with IC50s of 0.153 microM, 0.108 microM, 0.291 microM, respectively. EGFR/HER2/DHFR-IN-1 arrests cell cycle at G1/S and induces cells apoptosis[1].

O=C(C1=CSC2=NC=C(C3=CC=C(Br)C=C3)N21)NNC(C)=O

12352200