Bio-Connect

EGLN1 Polyclonal Antibody

RD82623A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman
TargetEGLN1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    EGLN1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID54583
  • Target name
    EGLN1
  • Target description
    egl-9 family hypoxia inducible factor 1
  • Target synonyms
    C1orf12; ECYT3; egl nine homolog 1; egl nine-like protein 1; HALAH; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; hypoxia-inducible factor prolyl hydroxylase 2; PHD2; prolyl hydroxylase domain-containing protein 2; SM20; zinc finger MYND domain-containing protein 6; ZMYND6
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203