EIF2AK2 (Ab-446) Antibody

Cusabio

EIF2AK2 (Ab-446) Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. Abujiang Pataer, et,al. (2002) Cancer Res ; 62: 2239. K. D. Ryman, et,al. (2005) J. Virol ; 79: 1487 - 1499. Susana Guerra, et,al. (2006) J. Biol. Chem ; 281: 18734 - 18745.

Human

-20°C or -80°C

12352203