ELAC2 Polyclonal Antibody

Reddot Biotech

ELAC2 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

ELAC2

elaC ribonuclease Z 2

COXPD17; elaC homolog 2; elaC homolog protein 2; elaC-like protein 2; ELC2; heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; zinc phosphodiesterase ELAC protein 2

Rabbit

IgG

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3 trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C

12352203