ELN-441958

MedChem Express

ELN-441958 [913064-47-8]

10

913064-47-8

Research Use Only

99.51

C29H29ClN4O2

501.02

ELN-441958 is a potent, neutral, competitive and selective bradykinin B1 receptor antagonist with a Ki of 0.26 nM against native human bradykinin B1 receptor. ELN-441958 has high oral bioavailability, and has low CNS exposure in the mouse[1].

ClC1=C2C(CN(C3=CC=CC(C(N4CCC5(CCN(C6=CC=NC=C6)CC5)CC4)=O)=C3)C2=O)=CC=C1

-20°C,2°C to 8°C

12352200