ELN318463 [851600-86-7]

TargetMol Chemicals

ELN318463 [851600-86-7]

72

851600-86-7

Chemical

Research Use Only

ELN318463

C19H20BrClN2O3S

471.8

ELN 318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised gamma-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyloid precursor protein (APP) selective gamma-secretase inhibitor.

3 years

Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)cc1)[C@@H]1CCCCNC1=O

-20°C

12352200