ELOVL1 Antibody, HRP conjugated

Cusabio

ELOVL1 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

ELOVL1

ELOVL fatty acid elongase 1

3-keto acyl-CoA synthase ELOVL1; CGI-88; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; elongation of very long chain fatty acids protein 1; ELOVL FA elongase 1; IKSHD; Ssc1; very long chain 3-ketoacyl-CoA synthase 1; very long chain 3-oxoacyl-CoA synthase 1

Rabbit

IgG

Elongation of very long chain fatty acids protein 1

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Human

-20°C or -80°C

12352203