Elubrixin [688763-64-6]
HY-18263A
CAS Number688763-64-6
Product group Chemicals
Molecular Weight463.31
Overview
- SupplierMedChem Express
- Product NameElubrixin [688763-64-6]
- Delivery Days Customer10
- CAS Number688763-64-6
- CertificationResearch Use Only
- Molecular FormulaC17H17Cl2FN4O4S
- Molecular Weight463.31
- Scientific DescriptionElubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[1][2][3].
- SMILESO=C(NC1=CC=C(Cl)C(S(=O)(N2CCNCC2)=O)=C1O)NC3=CC=CC(F)=C3Cl
- UNSPSC12352200