Elubrixin (tosylate) [960495-43-6]

MedChem Express

Elubrixin (tosylate) [960495-43-6]

9

960495-43-6

Research Use Only

99.78

C24H25Cl2FN4O7S2

635.51

Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[1][2][3].

O=C(NC1=CC=C(Cl)C(S(=O)(N2CCNCC2)=O)=C1O)NC3=CC=CC(F)=C3Cl.OS(=O)(C4=CC=C(C)C=C4)=O

2°C to 8°C

12352200