Elzovantinib (TPX-0022)

Selleck Chemicals

Elzovantinib (TPX-0022) [2271119-26-5]

9

Research Use Only

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Elzovantinib (TPX-0022, CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.

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