EM12-SO2F

MedChem Express

EM12-SO2F

14

Research Use Only

C13H11FN2O5S

326.30

EM12-SO2F is a powerful covalent inhibitor of CRBN through binding at His353. EM12-SO2F is a useful chemical probe to investigate the CRBN. EM12-SO2F inhibits the degradation of IKZF1 by lenalidomide (HY-A0003) in MOLT4 cells [1] [2]

O=S(C1=CC2=C(CN(C(CC3)C(NC3=O)=O)C2=O)C=C1)(F)=O

12352200