ENaC beta Antibody: RPE

Biorbyt

ENaC beta antibody

16

1 microg/ml of SPC-404 was sufficient for detection of beta-ENaC in 20 microg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000), IHC (1:100) ICC, IF, IHC, WB

Research Use Only

Polyclonal

1 mg/ml

RPE

Scnn1b

sodium channel epithelial 1 subunit beta

amiloride-sensitive sodium channel subunit beta; beta-ENaC; beta-NaCH; epithelial Na(+) channel subunit beta; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; sodium channel epithelial 1 beta subunit; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated, type I, beta

Rabbit

Amiloride-sensitive sodium channel subunit beta

Rabbit polyclonal to ENaC Beta (RPE). The Epithelial Sodium Channel (ENaC) is a membrane ion channel permeable to Na+ ions. It is located in the apical plasma membrane of epithelia in the kidneys, lung, colon, and other tissues where it plays a role in trans epithelial Na+-ion transport. Specifically Na+ transport via ENaC occurs across many epithelial surfaces, and plays a key role in regulating salt and water absorption. ENaCs are composed of three structurally related subunits that form a tetrameric channel, alpha, beta , and gamma. The expression of its alpha and beta subunits is enhanced as keratinocytes differentiate. The beta and gamma-ENaC subunits are essential for edema fluid to exert its maximal effect on net fluid absorption by distal lung epithelia(5). And it has been concluded that the subunits are differentially expressed in the retina of mice with ocular hypertension, therefore the up-regulation of alpha-ENaC proteins could serve as a protection mechanism against elevated intraocular pressure..

Amphibian, Hamster, Human, Mouse, Rat

See Manual

12352203