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Endoglin / CD105 (ENG/1621), CF640R conjugate, 0.1mg/mL [26628-22-8]

Endoglin / CD105 (ENG/1621), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401621
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence
Product group Antibodies
ReactivityEquine, Human, Monkey, Mouse, Porcine, Rat
TargetENG
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Overview

  • Supplier
    Biotium
  • Product Name
    Endoglin / CD105 (ENG/1621), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ENG/1621
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID2022
  • Target name
    ENG
  • Target description
    endoglin
  • Target synonyms
    CD105 antigen; END; endoglin; HHT1; ORW1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP17813
  • Protein Name
    Endoglin
  • Scientific Description
    CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Equine, Human, Monkey, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203