Enpp-1-IN-17

MedChem Express

Enpp-1-IN-17

14

Research Use Only

C18H24N4O2

328.41

Enpp-1-IN-17 (example 274) is a potent ENPP1 inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 microM and > 1 microM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4[1].

COC1=CC2=C(N3CCC4(CC3)CNCC4)N=CN=C2C=C1OC

12352200