Ent-(+)-Verticilide [2056011-05-1]

TargetMol Chemicals

Ent-(+)-Verticilide [2056011-05-1]

16

Research Use Only

C44H76N4O12

853.09

ent-(+)-verticilide is an effective and specific inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels, demonstrating antiarrhythmic properties. It suppresses RyR2-mediated diastolic Ca2+ leak and shows greater potency and a unique action mechanism compared to Dantrolene and Tetracaine. ent-(+)-verticilide serves as a valuable tool for exploring the therapeutic potential of addressing RyR2 hyperactivity in cardiac and neurological conditions [1].

C(CCCC)[C@H]1C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O1

-20°C

12352200