Western blot analysis of extracts from COLO205 cells, using P300/CBP antibody.
Western blot analysis of extracts from COLO205 cells, using P300/CBP antibody.
EP300/CREBBP Antibody
CSB-PA265859
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEP300
Overview
- SupplierCusabio
- Product NameEP300/CREBBP Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2033
- Target nameEP300
- Target descriptionE1A binding protein p300
- Target synonymsE1A-associated protein p300; E1A-binding protein, 300kD; histone acetyltransferase p300; histone butyryltransferase p300; histone crotonyltransferase p300; KAT3B; MKHK2; p300; p300 HAT; protein 2-hydroxyisobutyryltransferase p300; protein lactyltransferas p300; protein propionyltransferase p300; RSTS2
- HostRabbit
- IsotypeIgG
- Protein IDQ09472
- Protein NameHistone acetyltransferase p300
- Scientific DescriptionAcetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Gerd A. Blobel, J. Leukoc. Biol., Apr 2002; 71: 545. Eric Kalkhoven, Hum. Mol. Genet., Feb 2003; 12: 441 - 450. Wei-fang Shen, Mol. Cell. Biol., Nov 2001; 21: 7509 - 7522. Frederick C. Nucifora, Science, Mar 2001; 291: 2423.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203