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ProductsBack/EpCAM antibody [Ber-EP4]

EpCAM antibody [Ber-EP4]

Research Use Only
GTX01679
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetEPCAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    EpCAM antibody [Ber-EP4]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Ber-EP4
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4072
  • Target name
    EPCAM
  • Target description
    epithelial cell adhesion molecule
  • Target synonyms
    adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP16422
  • Protein Name
    Epithelial cell adhesion molecule
  • Scientific Description
    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Claudin-4 shows superior specificity for mesothelioma vs non-small-cell lung carcinoma compared with MOC-31 and Ber-EP4. Naso JR et al., 2020 Jun, Hum Pathol
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  • BerEP4 positivity in Merkel cell carcinoma: a potential diagnosis pitfall. Kervarrec T et al., 2020 Nov, J Eur Acad Dermatol Venereol
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  • Reactivity with the EpCAM-specific antibodies MOC-31 and Ber-Ep4 in plasma cell neoplasms: a potential diagnostic pitfall in cytology samples. Weimholt RC et al., 2019 Sep-Oct, J Am Soc Cytopathol
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  • The impact of crosslinking and non-crosslinking fixatives on antigen retrieval and immunohistochemistry. Stumptner C et al., 2019 Sep 25, N Biotechnol
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  • Clinical and pathological characteristic of metastatic malignant mesothelioma initially diagnosed by lymph node biopsy. Zhu XL et al., 2017 Jun, Pathol Res Pract
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  • Primary cutaneous cribriform carcinoma: report of six cases with clinicopathologic data and immunohistochemical profile. Arps DP et al., 2015 Jun, J Cutan Pathol
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