EpCAM antibody [MOC-31]
GTX01685
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEPCAM
Overview
- SupplierGeneTex
- Product NameEpCAM antibody [MOC-31]
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with a transmembrane glycoprotein present on most glandular epithelium and tumors originating from such epithelium. This antibody has been used to distinguish adenocarcinoma from mesothelioma and hepatocellular carcinoma. This antibod
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMOC-31
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4072
- Target nameEPCAM
- Target descriptionepithelial cell adhesion molecule
- Target synonymsadenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1
- HostMouse
- IsotypeIgG1
- Protein IDP16422
- Protein NameEpithelial cell adhesion molecule
- Scientific DescriptionThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Claudin-4 shows superior specificity for mesothelioma vs non-small-cell lung carcinoma compared with MOC-31 and Ber-EP4. Naso JR et al., 2020 Jun, Hum PatholRead more
- Immunohistochemical Expression Analysis of EpCAM in Hepatoblastomas. Lopez-Nunez O et al., 2020 Oct, Appl Immunohistochem Mol MorpholRead more
- EpCAM (MOC-31) - immunohistochemical profile and clinico-pathological correlations in different histological variants of papillary thyroid carcinoma. Andriescu EC et al., 2019, Rom J Morphol EmbryolRead more
- Anti-EpCAM antibodies for detection of metastatic carcinoma in effusions and peritoneal wash. Carneiro FP et al., 2019 Aug, Oncol LettRead more
- Reactivity with the EpCAM-specific antibodies MOC-31 and Ber-Ep4 in plasma cell neoplasms: a potential diagnostic pitfall in cytology samples. Weimholt RC et al., 2019 Sep-Oct, J Am Soc CytopatholRead more