EPhA3 Protein, Canine, Recombinant (His)

TargetMol Chemicals

EPhA3 Protein, Canine, Recombinant (His)

16

Research Use Only

58.97 kDa (predicted). Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.

Erythropoietin-producing hepatocellular carcinoma cell surface type-A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (-295~-261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.

-20°C

12352200