ER degrader 7 [2922929-63-1]

TargetMol Chemicals

ER degrader 7 [2922929-63-1]

16

Chemical

Research Use Only

ER degrader 7

C33H31F4N3O5SSe

736.63

ER degrader 7 (Compound 35t) is a selective degrader of both ERalpha and ERbeta and functions as a tubulin polymerization inhibitor. It inhibits cell viability with IC50 values of 0.06 microM for MCF-7, 2.56 microM for T47D, 15.84 microM for MCF-10A, 1.59 microM for LCC2, 1.67 microM for T47D D538G, and 1.37 microM for T47D Y537S cells. Additionally, ER degrader 7 demonstrates efficacy in suppressing breast cancer tumor growth [1].

3 years

S(N(CC(F)(F)F)C1=C(F)C=CC=C1)(=O)(=O)C2C3C(=C(C(O3)C2)C4=CC=C(O)C=C4)C5=CC=C(NC(CCCCC[Se]C#N)=O)C=C5

-20°C

51202000